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CIRCALYS® - Chrono detox - Feel good energizer
- Concept of chronobiology
- Brain-skin axis modulation
- Psychobiological approach
CIRCALYS® is a natural active ingredient titrated in andrographolide extracted from the leaves of Andrographis paniculata, a major detoxifying plant in Ayurveda.
CIRCALYS® modulates skin circadian clock, by restoring a "young" invigorating clock gene expression profile in old/tired keratinocytes and by acting on circadian modulators related to key cellular pathways. CIRCALYS® extends cell longevity, reduces cell damages, promoting skin revitalization. CIRCALYS® also acts as a "Brain-Skin" axis booster, enhancing oxytocin, endocannabinoid and endorphin signaling pathways to relax skin.
Clinically tested on night/shift workers during 28 days, CIRCALYS® was proved to significantly reduce facial visible signs of fatigue (eye bags, dark circles, under-eye wrinkles, dull tone) and the impacts of fatigue on mood: the feeling of well-being was boosted, the perceived stress and the negative affect were reduced ("yoga-like" effect). CIRCALYS® is a chrono-detox active ingredient providing a "feel good energizing" effect.